Popular Drink Can Help Lower Breast Cancer Risk - CBS Local

istockphoto Revealing SeanALee For more trusted health Media and information, visit CBS Detroit's DETROIT (WWJ) a' Some thing many women have each and every day might help reduce the risk of breast cancer returning in recovering patients. A fresh research out of Sweden sees drinking two cups of coffee per day could end breast cancer from recurring. Researchers viewed 600 cases over a five year period. They found that when combined with the anti-cancer drug tamoxifen, coffee slice the rate of breast cancer recurrence by half. The analysis authors arenat exactly certain how coffee interacts with tamoxifen, however they think it could make the drug work better. Itas maybe not the initial study to link coffee use with cancer risk reduction. Harvard researchers found women and men who drank three or even more cups of coffee a day reduced their threat of developing specific kinds of skin cancer.

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Animal study finds deep brain stimulation reduces binge eating behavior

Stimulating a region of the brain known to be involved in reward decreases binge eating behavior in mice, according to a study published in the April 24 issue of The Journal of Neuroscience. The findings add to a growing body of evidence supporting the role of the brain's reward system in driving the consumption of palatable food. It could one day pave the way for more effective and lasting treatments for obesity.

The numbers of people worldwide living with obesity continues to climb. Recent studies suggest that the consumption of high calorie foods activates regions of the brain associated with reward. As a result, scientists are increasingly interested in understanding how changes taking place in the brain may be responsible for driving individuals to consume more calories than needed.

In the current study, Tracy Bale, PhD, and colleagues at the University of Pennsylvania set out to see if activating the nucleus accumbens - a region of the brain involved in the promotion of motivational behaviors - would alter binge-eating behavior in mice. The researchers used a technique called deep-brain stimulation (DBS) to directly deliver electrical impulses to the nucleus accumbens of mice that regularly binged on their food (ate 25 percent of their daily caloric intake within one hour). While mice that did not receive DBS showed little change in their eating habits, DBS significantly lessened the others' interest in binging on high fat food.

"Little is currently known about the neurobiological mechanisms of binge eating, and there are few effective treatments," explained Paul Kenny, PhD, who studies addiction at the Scripps Research Institute and was not involved in this particular study. "This study provides insights into the mechanisms that play a role in binge eating," he added.

Bale's group also tested the long-term effects of DBS on obese mice that were given unlimited access to high-fat food. After four days of continuous DBS, the obese mice consumed fewer calories and their body weight dropped.

"Overall, these studies indicate that activity in the reward centers of the brain may be a critical component driving individuals to overeat despite known negative health consequences," Bale said. "These results are very exciting as they provide our best evidence yet that we might be able to modify specific behaviors linked with body weight changes and obesity," she added.

Future clinical trials will need to explore the effectiveness of DBS in reducing obesity in people before researchers know whether or not DBS presents a viable treatment option for the millions worldwide living with obesity. However, as noted by lead study author Casey Halpern, MD, a neurosurgeon at the University of Pennsylvania, DBS targeting other areas of the brain is currently used to treat Parkinson's disease, and is being tested in clinical trials for the treatment of depression, obsessive-compulsive disorder, and addiction.

"Once replicated in human clinical trials, DBS could rapidly become a treatment for people with obesity due to the extensive groundwork already established in other disease areas," Halpern said.

The research was supported by the National Institute on Drug Abuse and the National Heart, Lung, and Blood Institute.

The Journal of Neuroscience is published by the Society for Neuroscience, an organization of nearly 42,000 basic scientists and clinicians who study the brain and nervous system. Bale can be reached at .

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Dealing with cancer: A bold new professional world - Fortune

By Vickie Elmer FORTUNE a' Recently, the word "cancer" was off limits, among friends, at home, and truly at work. Whether it was out of superstition, concern, dilemma, or regard, many talk about the disease was done in hushed tones. Today, whilst the survival rate climbs, the decisions people make after examination -- both personal and professional -- have evolved somewhat. Abruptly, for several (but not all), the issue isn't, "How do I leave work for good?" Rather, it is "How long do I take off?" or "Do I have to lose at all?" Working following a cancer diagnosis is becoming fairly common, based on a brand new study done by the nonprofit group Cancer and Careers. One in four individuals with cancer who were questioned said they continued trying to keep their health insurance. Twice as many said they worked to keep things "as normal as possible." And two-thirds have been questioned stated they felt well enough to remain at work. AThe Harris Interactive survey queried 400 adults identified as having cancer have been working. "Work offers a to them from cancer-land," explained Kate Sweeney, executive director of Careers and Cancer, a nonprofit that offers resources to employees. MORE: Apple and Tim Cook's next actions Some 45% of individuals said they took virtually no time off after their examination, and kept operating, while 31% said they took ranging from 2-3 weeks to five weeks off, in accordance with Cancer and Careers' review. More companies must cope with relatively new area, as more employees choose to continue working. TIME specialist Margaret Spence says she has seen all types of responses from organizations with workers diagnosed with cancer. Spence says it's possible for individuals and organizations to feel stuck. "Employers are found between a rock and a difficult place," especially because they do not always have a whole picture of the worker's health, she said. This past year, Spence's man was clinically determined to have a rare type of cancer -- and she got to experience the cancer-career conundrum up close. The couple considered relocating temporarily to New York or Texas to be nearer to good quality treatment but decided that out because of the related costs. "He had a need to hold working," Spence said. "It was the one thing that held him connected" to the entire world amid rounds of radiation. Around 13.7 million folks have had cancer and were living in the United States Of America in 2012, and that is expected to increase to 17.8 million by 2022, based on the American Cancer Society. One-quarter of male survivors and about one-third of feminine cancer survivors are under 60 years of age, while another 25% are 60 to 69. Cancer does have a toll on people's careers. Survivors are 4 -5% less prone to hold jobs and work around four hours less than similarly aged people with out a history of cancer, in accordance with study from Penn State. And, probably without surprise, those who suffer from recurrences of cancer work less and take longer breaks from work. Workers today are more ready to discuss the details of their disease with managers and coworkers than these were 10 years ago, Sweeney said. Ten years before, many people held their cancer a secret at the job, she claims. Companies are taken by more: Employees with cancer to process However, maybe not everyone is comfortable discussing infection on the job. Spence told of a customer of hers who was a senior manager at an agricultural organization. One day, she left deals for Spence and a few the others before leaving for what her colleagues thought was a week's vacation. Three days later she examined in to surgery and died. "I was in shock when I consequently found out. I had no notion she was sick," Spence said. Spence feels companies belong to two major categories: those that follow sick leave or disability policy and regulations strictly and those that treat employees like individuals and assist them in their treatment. Most of the decisions are created one-by-one based on the employee's knowledge, value, and treatment. "It is extremely particular. If an employer really loves the staff, that is when they tend to be more flexible or more sympathetic," said Kate Brown, director of support and advocacy at Lungevity, a lung cancer support charitable. Lungevity's Brown says that some workplaces arrange "meal trains" where different people deliver a meal each week to an associate with cancer. A special telephone was bought by another, she says, with speakers therefore an employee whose voice was hoarse and dim might continue steadily to field calls. Many corporate plans are based on national laws and requirements, including rooms mandated by the Americans with Disabilities Act.A Cancer was added to the set of diseases covered by the ADA on Jan. 1, 2009, and the EEOC issued guidelines because of it several years later. Firms with more than 50 employees must give Family and Medical Leave to employees who've cancer. Beneath the FMLA, individuals are entitled to 12 months of unpaid time off to take care of a kid, partner, or themselves. The employer is likely to carry on medical health insurance and hold a comparable job open for these personnel. MORE: Why GE is betting on software At Cancer and Careers, the staff is beginning to hear more from employers seeking to help workers through their cancer diagnosis and treatment. Sweeney urges firms to be variable and allowing staff to work at home throughout chemotherapy or radiation. Some organizations are creating "shared holiday pools" to ensure that employees with additional days can offer them to colleagues struggling cancer or other serious illnesses. Businesses wish to hold onto knowledgeable team, therefore the portion of U.S. firms that provide cancer insurance plans has inched up to 34% (from 28% in 2008), according to the Society of Human Resource Management. "These personnel are valuable," and employers often desire to find approaches to bring them back again to work, mentioned Tom Parry, leader of the Integral Benefits Institute, an independent research firm. Other employees are watching carefully how a employer treats them. "When companies do the best thing with some body with cancer, that is a very important message" that resonates with many employee, he said.

Progress in Diabetes Care in US, but Still a Way to Go - Medscape - Medscape

A new "diabetes report card" chronicling how the United States is faring in terms of management of the condition in adults, based on data to 2010, shows that there has been improvement, but there are still large gaps in terms of the control of 2 important risk factors, smoking and hypertension.

The data "provide a nationally representative snapshot of risk-factor control and preventive practices" with regard to both type 1 and type 2 diabetes, say the researchers in their article in the April 25 issue of the New England Journal of Medicine.

"The take-home for me is that we are doing better," lead author Mohammed K. Ali, MB, ChB, from the Centers for Disease Control and Prevention, Atlanta, Georgia, told Medscape Medical News. "The improvements, especially for glucose and cholesterol control, are pretty evident, and we are also getting more and more people to come back for their preventive-care visits — for annual eye exams, flu vaccinations, and such."

But "the big gaping hole that we are not really doing a good job with is blood-pressure control and tobacco," he added. "One in 5 Americans with diabetes still smokes, and that's high, and there has literally been no change in the past 12 years, and that's quite disappointing. We are not doing enough to counsel patients in terms of quitting smoking."

The researchers assessed data from adults with self-reported type 1 or type 2 diabetes from the National Health and Nutrition Examination Survey (NHANES) and the Behavioral Risk Factor Surveillance System to examine risk-factor control, preventive practices, and risk scores for coronary heart disease from 1999 to 2010.

Over this time period, the weighted proportion of survey participants who met recommended goals for diabetes care increased by 7.9 percentage points for glycemic control (HbA1c < 7.0%), 9.4 percentage points for individualized glycemic targets, 11.7 percentage points for blood pressure (< 130/80 mm Hg), and 20.8 percentage points for lipid levels (LDL cholesterol < 100 mg/dL [2.6 mmol/L]).

The changes in numbers of people reaching glycemic control and cholesterol goals were significant (P = .009 and < .001, respectively), but for the blood-pressure target, this was not the case (P = .08).

Tobacco use did not change significantly, either (P = .96), but the 10-year probability of coronary heart disease decreased by 2.8 to 3.7 percentage points.

Still, almost 30% to 50% of adults with diabetes did not meet targets for glycemic control, BP, or lipid control, and only 14.3% met the targets for all 3 of these measures and for tobacco use, the authors note.

However, Dr. Ali said that when they assessed people in terms of individualized HbA1c targets, "something there has been a renewed emphasis on, from all of the major diabetes organizations, such as the American Diabetes Association and European Association for the Study of Diabetes, it wasn't just 50% now meeting the goal of an HbA1c under 7, it was something like two thirds of all adults with diabetes actually meeting their respective [individualized] goals.

"The key for us now is that this is just a start," he stressed. "We've tried to lay a foundation of saying this is probably what's going on in terms of control. Now what's needed is more research, where you actually follow those same people into the future, with a really well-designed study, to see whether those different levels of control for different risk groups actually result in fewer heart attacks and strokes" and other outcomes of interest such as retinopathy and chronic kidney disease, he said.

In an accompanying editorial, Graham T. McMahon, MD, MMSc, and Robert G. Dluhy, MD, from the division of endocrinology, diabetes, and hypertension, Brigham and Women's Hospital, Boston, Massachusetts, call the gains reported by Dr. Ali and colleagues "modest" and point out "there's a long way to go to deliver the quality of diabetes care that truly meets our patients' needs." To achieve this, there needs to be a move from "episodic care" for diabetes to a chronic care model, they stress.

Dr. Ali concurs. "Team-based care for chronic diseases is really the way we should be moving into the future," he told Medscape Medical News. Doctors, he said, don't always have the time to address behavioral change like smoking cessation and also "may not always have the best skills to deal with something that is behavioral and requires so much counseling." Allied healthcare professionals such as nurse practitioners can be hugely beneficial in this instance, "because they can spend much more time with a patient to achieve a behavior change like tobacco control," he explained.

Drs. McMahon and Dluhy add that patients too need to become collaborators in this model of care for chronic diseases, "and physicians need to become comfortable with sharing responsibility" with other healthcare providers. Curricular changes across the continuum of training "are helping new physicians to develop the skills required to facilitate these changes in practice," they observe.

And such change is needed, not least because diabetes costs the economy so much, Dr. Ali added. "The gaps we are not attaining, they are really costly. Diabetes is one of the biggest contributors to healthcare costs in the US. If we could work on these very preventable causes of mortality, the tobacco and the blood-pressure control, it's likely we will see large reductions in spending."

Dr. Ali and coauthors have reported no relevant financial relationships. Dr. McMahon is the medical education editor and Dr. Dluhy is an associate editor for the New England Journal of Medicine.

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Hospitals cite diets as gallbladder amputations reported among youth - China Post

Three young men aged 15 to 17 who complained of abdominal pains were diagnosed to be suffering from acute cholecystitis and gallstones, resulting in the removal of their gallbladders, according to the Chung Hsiao branch of Taipei City Hospital (北市聯合醫院忠孝院區). Doctors said these conditions typically afflict pregnant women and people aged over 40, adding that it is quite alarming to find occurrences of gallbladder-related disease among young people.

According to statistics, among women above 40 years of age, 20-30 percent suffer from gallstones due to hormonal changes relating to pregnancy, with occurrence of gallstones reported among 10-20 percent of men in the same age group. Studies also indicate that most gallstones are formed by cholesterol, not calcium.

According to reports, the three young men are all slightly overweight, with a body mass index rated of 30, and all exhibited a penchant for foods with high sugar and fat levels. In addition, the young men preferred beverages with high sugar content. Doctors also indicated that the young men had been self-medicating with over-the-counter drugs for upset stomachs, which delayed treatment and exacerbated their conditions. The removal of the gallbladder can have severe lifelong consequences, as a person's digestive system may longer be able to process foods containing fat without them.

In addition to committing to healthier dietary choices, doctors listed the excessive consumption of oily foods, a lack of water intake, and skipping breakfast as the primary causes of gallbladder disease among the young. Doctors recommend the youth to drink at least 1.5 liters of water a day, and avoid tea and coffee.

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Cycling for Fitness

actions, alternative ideas, workout, Weight Loss Journal, exercises Professional competitors speak about some thing called spinning. Spinning is just a expression for the absolute most efficient solution to pedal. You pedal in a full circle, meaning taking up with your feet as well as moving. A lot of people who ride bicycles know of pedaling only as pushing down on the pedals. Really, this is only 50% reliable. But using the feet to pull while also pushing, you gain that much more energy per stroke on the pedals. In addition, it provides an infinitely more even workout for the legs, and provides a simpler overall movement while riding. Getting the hang of alternating involving the left and right leg and from just pushing to pushing and pulling will require some exercise, nevertheless the rewards are worth it. Working more of your feet and you'll pedal more efficiently and more powerfully, while using less power. It is an all over winning condition. - You need to be rotating at around 90 or more RPM, or revolutions each and every minute. What this implies is that you're in the low gear, and the feet happen to be turning really fast. The spin can be practiced by you really early throughout the season with 120 RPM, and that is going to show your feet to be quicker. There are small bike computers that you can purchase from local bike stores that are planning to tell you just how fast you are actually rotating. At between $20 and $30, they're really beneficial and eventually be described as a certainly useful tool for education. - A great way that you can gauge the improvements that you make is always to keep on operating the exact same loop or to drive a number of different loops that you can easily replicate. You is going about timing your trip, after you go the first week of training and training. The computer should also be effective at getting used as a timer, and it's going to inform you what your average speed is. You may not necessarily need certainly to ride in order to improve your time over these first handful of days. Rather, you ought to be riding strictly for the experience and the enjoyment. - The first few weeks of riding should be between half an long and three quarters of an hour long. You may have some small hills in your experience, and you might actually should try to learn just how to start driving while standing up. you wind up coming to a hill and if you are operating at the 90 RPM pace as I advised, your cadence will probably reduce naturally. By standing on the pedals, however, you'll manage to give your self more power, keeping the same gear while you climb the mountain. More next time! Photo Credits: It isGreg Actually published 2009-11-09 03:40:59. Republished by Post Advocate Categories: Tags:

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Clues to Cancer: Plain Dealer series follows patients as they join doctors on ... - Plain Dealer

If the experimental cancer drugs these nine individuals took while participating in early-phase clinical trials turn into breakthrough treatments, we owe them each a huge debt of gratitude.

And if it turns out that those drugs don't advance the ongoing quest to stop cancer in its tracks, we still owe these people for that knowledge.

All of them volunteered for Phase 1 cancer clinical trials at University Hospitals Seidman Cancer Center. These studies are the first step in determining if drugs and other therapies are safe in humans.

When their respective cancers no longer responded to standard treatment, they agreed to take drugs not yet approved by the U.S. Food and Drug Administration except for use in a study.

For the past 10 months, The Plain Dealer followed these patients through their journey as study participants in seven different Phase 1 trials at UH.

Undaunted that he would wear the "first-ever" label for his Phase 1 clinical trial, Vince Petro, 60, of Ashtabula, made his decision quickly.

Faced with what to do following his November 2011 surgery to remove an aggressive brain tumor, oncologists hoped he would agree to try a new stem cell gene therapy first conceived at Case Western Reserve University.

UH physicians had been looking for a patient to enroll in that trial for most of 2011. For them, Petro personified the opportunity to see whether the gene therapy that had showed promise in mice and dogs -- allowing them to tolerate stronger doses of cancer-fighting drugs -- would do the same in humans.

Not all of the patients The Plain Dealer followed are still alive. Last October, Janet Whitney of Brecksville and John Soley of Massillon died within one day of each other.

Their families talked about how the lives of others might change because of their loved ones' willingness to volunteer.

"She was always thinking about other people," said Andrea Whitney, Janet Whitney's daughter. "I think there's a part of you, when someone you love is gone, you want to know all of the impacts they've had in the world."

"He didn't want anyone else to suffer through this," Jeannie Soley said of the pancreatic cancer he had lived with since 2008. "That's what it was all about."

We almost never get to know the names of people who take part in early-phase studies that are crucial to new drug development, studies that emerge on the heels of promising laboratory research that is years in the making.

By the time the FDA approves a drug for widespread marketing and clinical use, hundreds -- sometimes thousands -- of patients have taken it.

But the number of patients involved in Phase 1 studies is small. And they largely remain anonymous, as do many of the countless scientists working in research labs where drug development begins; the physicians who are instrumental in designing and conducting the studies; the oncologists and nurses and others who provide patient care; the people who produce the consent forms that make the studies understandable to patients; the data and lab managers who collect and interpret information from studies.

UH is the lead institution for early-phase drug development at Case Comprehensive Cancer Center, a collaboration that includes the Cleveland Clinic and is based at Case Western Reserve University.

Case Comprehensive is one of just 14 centers to receive a multiyear grant from the National Cancer Institute to support its Phase 1 program. It is also part of a relatively new drug pipeline: The NCI picked Case Comprehensive researchers to use NCI-developed drugs in early-phase trials they design and run. Case Comprehensive is one of seven centers in the country with that distinction.

Case Comprehensive is also part of a larger network of hospitals, pharmaceutical companies, private organizations and governmental agencies that pursue cutting-edge science that has the potential to be tested in Phase 1 trials and evolve into effective cancer-fighting agents.

Drug development is a long road. Because of people such as Carl Gehringer Jr., Barbara Malone, Margene Manning, Latanga Nash, Vince Petro, Georgine Riley, John Soley, Larry Tremaglio and Janet Whitney, part of that road continues to run through Cleveland.

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Weight Loss Tips and Tricks

When it comes to losing weight, you probably know the drill. Burn more calories than you consume, eat healthy, and be healthy and the results will happen. Most diets and weight loss plans do not have much substance which is why dieting in general is far from healthy for you. Here are some weight loss tips and tricks that are going to steer your weight loss efforts in the right direction. Follow these cardinal rules of weight loss and you will be healthy and happy in no time at all.

1 - Drink enough water after breakfast. Water should absolutely be your primary drink following breakfast. Drink milk or orange juice in the morning, and then focus on water rather than a sugar laden drink like soda or juice. The average person in America consumes as many as 245 calories a day just in drinks. That translates to a gain of 25 lbs every year!

2 - Keep a notebook with you so that you can track what you eat. You do not necessarily have to count calories, but what you do have to do is keep track of everything that you are consuming. The reason for this is so that you can keep track of what you are eating and how it impacts you throughout the day. Many people do not realize how much food and other garbage they are putting into their mouths until they start consciously tracking everything that they eat.

3 - Purchase a pedometer so that you can keep track of your steps per day, and try to achieve an additional 1,000 to 2,000 steps per day. This is especially important if you are sedentary, meaning that most of your day is spend in a seated position. Continue to challenge yourself by adding more and more steps every day and you will see the pounds coming off before you know it.

4 - Rather than eating three normal sized meals in a day, consider breaking your meals down smaller and consuming between five and six meals a day instead. When you break your meals into intervals, studies have shown that you can cut down your calorie consumption by as much as 30 percent over the course of a day, and this is going to lead to weight loss on a consistent basis if you continue to eat in this way.

5 - Walk for at least 30 minutes every single day. 30 minutes of daily walking is enough to prevent weight gain, and if you add more to that, you will be burning calories and losing weight. Exercise beyond the traditionally recommended 30 minutes is going to result in fat loss and weight loss for optimum health, which is what you should be aiming for.

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Weight Reduction Methods and Tricks

fat reduction, Weight Loss Journal When it comes to losing weight, you probably know the routine. Burn up more calories than you consume, consume healthy, and be healthy and the outcomes will happen. Most food diets and weight loss programs don't have much substance which explains why dieting generally is far from healthy for you personally. Here are some weight loss hints and tips that are likely to steer your weight loss attempts in the proper path. Follow these primary principles of weight loss and you will be healthier and happy right away at all. 1 - Drink enough water after break fast. Water should definitely be much of your drink following breakfast. Drink milk or orange juice each morning, and then focus on water rather than sugar stuffed drink like soft drink or juice. Calories are consumed as many as 245 by the average person in America a day just in drinks. That means a gain of 25 pounds every year! 2 - Keep a notebook with you in order that you can observe what you eat. You don't necessarily have to count calories, but what you do have to complete is keep an eye on everything that you are eating. The reason behind this is to ensure that you could keep an eye on what you are consuming and how it impacts you throughout the day. Many individuals don't realize until they start knowingly monitoring exactly what they eat how much food and other trash they are putting into their mouths. 3 - Purchase a pedometer so that you can keep track of your steps per day, and attempt to achieve one more 1000 to 2000 steps per day. If you're inactive, meaning that nearly all of every day is spend in a seated position this really is particularly essential. Continue to challenge yourself by the addition of more and more ways every day and you will start to see the pounds coming off before it is known by you. 4 - In the place of eating three normal sized meals in a, contemplate breaking your meals down smaller and consuming between five and six meals a day instead. When you break your diet into periods, studies demonstrate that you can cut down your calories from fat by around 30 percent over the course of each day, and this is going to lead to weight reduction on a regular basis if you continue steadily to eat in this way. 5 - Walk for at the very least thirty minutes everyday. Half an hour of daily walking is sufficient to avoid weight gain, and you'll be losing weight and burning calories, if you add more to that. Workout beyond the traditionally recommended 30 minutes will probably bring about fat loss and weight loss for perfect health, that is what you need to be aiming for. Photograph Credits: Edward Yourdon Actually placed 2009-11-30 03:52:37. Republished by Article Promoter Categories: Tags:

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Sofia Vergara starts up about struggle with thyroid cancer - Fox News

Sofia Vergara is known for her role while the bubbly, trophy wife Gloria on the hit TV show aModern Family.a ABut 13 years ago, she played another significant role: cancer patient. When she was only 28 years of age, Vergara was identified as having thyroid cancer. aGoing through the entire means of getting my thyroid out, then a radiation and all the stuff, obviously you change your daily life a' because your priorities change,a Vergara, 40, told FoxNews.com. AaYou understand that regardless of how much splendor, money, success you've a if you donat have health, you have nothing, because you canat do anything.a The thyroid gland is a butterfly-shaped organ located at the front of the throat. AIt produces hormones that regulate metabolic process, heart rate, blood pressure and body temperature. Related: Celebs With Thyroid Conditions According to the National Institutes of Health, thyroid disorders have increased in the United States over the past two decades. A study published in the Journal of the American Medical Association, found that thyroid cancer is becoming more common in the U.S., growing by 140 % between 1973 and 2002. However, thyroid cancer is treatable generally. Having her thyroid removed left Vergara with hypothyroidism a' a condition in which the thyroid gland doesn't make of certain important hormones. AShe relies on daily medication, which produces an artificial kind of these hormones. aItas having a relationship with your doctor,a Vergara said of working with hypothyroidism. AaHaving an item like the one I get, Synthroid, Iave never had an issue, never had symptoms.a Now, Vergara is increasing awareness about her life that was changed by the disease. AAs part of her understanding campaign, Vergara gives her story on http://www.followthescriptcampaign.com/. AThe site helps people learn more about thyroid disorders, connect to the hypothyroidism neighborhood and get more information about the best treatments. aYou could possibly get along with it really easily,a Vergara said. AaIt is not something which will probably invest some time to go and get examined, therefore I donat there is a reason why anyone must be coping with hypothyroidism.a

Link: Tackling Diet, Exercise Together Produces Best Results: Study

Getting Encouraged the Right Way

objectives, healthier eating, determination One of many key elements to eating right is getting motivated. There is just no point, should you choose not have enough drive to accomplish the continue, whilst it is easy enough at first to have great ideas. In order to make sure that you are successful together with your diet, you're going to need to make sure that your priorities are in order and that you've the best kind of determination. Before you actually start your daily diet, we suggest building a set of all the items that you desire to accomplish. Divide these in to three columns: Appearance, Human body Health, Activities. Now, you will end up able to see all of the issues using one sheet of paper. This makes it a lot easier to keep your aims right in front of you. Redo your list, once you've them down and prioritize the things that would be the most significant to you. As an example, if reducing your blood pressure is just a high priority, go that to the top of the health record. Make a master list which has them in order of importance, once you have all of your products prioritized in each line. You'll be referring back once again to this as you begin to generally meet your aims. By putting it in writing, you are giving that visualization to yourself that makes it much easier to see your goals and meet them. While it's wonderful to help keep it in your head, many people prefer having a hard copy. It really is an excellent experience, when you begin to always check those things off as goals achieved. Therefore, given that you've your list done, you're prepared to start on your diet plan. Make sure that you choose one that can make it simple to keep your goals at first. Rome wasn't built-in each day and time is taken by a good diet to work. Do not doom yourself to failure by going on an excessive diet that you have no hope of maintaining. Start small and work the right path up. You'll be considered a lot more unlikely to call it quits after having a day or two and you'll be able to keep motivated. One great way to start small is simply by reducing a few of the foods you eat or drink everyday which contain empty calories. Pop is the best spot to start since you'll generally see very quick results. Decide to try reducing 1 or 2 each day initially, and then raise the amount before you are no more drinking it. The outcomes you see will keep you motivated and you'll maybe not be depriving your self of it all at the same time. When you feel as if you want to quit with your diet, take out that record and re-read it. See what you have crossed out and tell yourself that these are your life that will be changed by important goals. It's easy to leave and leave, but you'll be paying the purchase price for it for the others of one's life. Image Credits: 1 Originally posted 2008-05-21 05:33:02. Republished by Blog Post Advocate Categories: Tags:

Emergiblog

I am perhaps not militant. I'm not a heart, I donat grasp every cause du jour, nor do I go on what someone termed a vehicle of supportersa for whatever happens to perform over the blogosphere on certain time. As you'll find in this world I'm as straight-arrow, by-the-book, trust-the-Establishment. When I say when I say that I'd decide to try the roads about something that's happenedawhen I say that I'm questioning anything I thought I knew about power that I'm reeling;, poweraand nursinga Iam perhaps not bluffing, over-reacting or being hysterical. Excuse my unprofessional language, but there's some bad s*** heading down in Arizona. ********** The Arizona Board of Nursing has gone from ridiculous to abusive in the Amanda Trujillo case. It wasnat bad enough that they thought clicking a field on some type of computer that might order an incident management hospice consult must mean enduring: (a) a detailed interrogation about every facet of your entire career, (b) or that speaking about your position should result in a psychiatric assessment, including acquiring signed releases from your entire doctors going back six years and seeing a panel appointed PhD. Yes, pressing that package meant giving up protected HIPAA data to all! I canat replicate that enough, itas that dreadful. But thatas old media, isnat it? Hereas the brand new stuff. ******** A letter was received by amanda from her university declaring they certainly were educated by the AZBoN that her license was under study. However, old information, you say? But wait! A Board staff member wrote a letter questioning it! At Amandaas demand to keep the name of her university out from the focus, Iave perhaps not listed it here. I've seen: (a the letter from her college stating they were anotified by the AZ Board of Nursing that your license is under investigationa (thatas a primary offer, italics mine.) Not that they looked it up, not that they deduced, but that they were notified. (b) Iave seen the BoN letter requesting proof of her presence and, (d) Iave noticed the BoN letter from a staff member who aanot aware and is declines reporting it of any other Board staff member performing so.a (Italics mine.) Usually are not the hell did? Amandaas school was informed by some one at the Board. A request for confirmation of presence is not a notification that a is aunder investigation.a Nowhere on the letter for confirmation does it say or personal that the license is aunder investigation.a But it gets bettera ******** Amanda is now being charged with applying false aacademic credentialsa! Yeah, this is what you do when (a) the initial costs arenat legitimate, (b) youare angry that somebody had the ovaries to perhaps not forget and stay up for herself, (c) they werenat intimidated by the psychological examination, and (d) you have to ramp up the intimidation factor. And the letters were seen by Iave for this, also. Amanda was accepted in to a different universityas Acute Care Nurse Practitioner doctoral nursing system in nov 2010. She began utilising the designation aSa after the professional designation, to signify aStudenta on the auto sig on her email. Because of surgery that was included by some major health issues, Amanda was struggling to begin this program. In November of 2010, she resigned from her job at the Mountain Vista Infirmary, using her private email. She'd forgotten to just take the aDACNP-Sa off the aMSN, RN, DACNP-Sa of her private mail vehicle sig. ******** So that they are investigating this, per the Nurse Practice Act, for deceiving, hurting or defrauding the public and/or expressing or inferring she was a practitioner through the usage of the initials. Boy, I really hope all of the public damaged by those six initials on her personal e-mail sought help. The Board found this terrible, egregious activity of professional malfeasance throughout their acutely detailed study of Amandaas career. For the history, the Arizona Board uses an average of 7 weeks investigating the average criticism, which hours are averaged 17 by them (see this open letter to Arizonaas governor, by RN Greg Mercer.) They should really be gunning for something here. If they had something on the initial problem, this might have already been over well before now. What the hell is certainly going on? ******** And letas remember what brought this all on. Patient education and a recommendation for an incident management hospital consult. No harm. No death. No tort. An informed patient. A change of heart. A fuming physician. And the nursing administration at Banner Del E. Webb Clinic, who feels that patient advocacy is something to be reported and tried to the Arizona Board of Nursing. And obviously the Arizona Board of Nursing doesnat simply take kindly to being questioned and operating out on view. Meanwhile, the American Nurses Association is amonitoring closelya and the Arizona Nurses Association is working hard for the nurses of Arizona, but canat help someone nurse who's under investigation. ******** Iam not here telling anybody they should support Amanda. Whether you are for her or against her or couldnat care less one way or another, so be it. It is a damn frightening story. What's scarier to me is the proven fact that Amanda must have closed up, kept her head down and just tried to get another job. Is that what nursing is approximately? Are we so whipped by needing our paychecks that we donat dare speak out about something, anywhere, anytime? The nurses in Texas talked out and there clearly was support from all around the country. Does a nurse must be charged before anybody cares? ********* Something bad is happening in Arizona. From the places of Banner Health, to the inner workings of the Arizona Board of Nursing, something is wrong. You are able to dismiss it, vilify Amanda, write her down as aoh there must be anything elsea, or make fun of those people who do support her, nevertheless the fact is this isn't right. If Iam wrong, then Iam wrong and Iall function as the first to publish it. Iam maybe not wrong. When Nurses Strike At the Greatest Levels: A Obvious Abuse of Power

'Health MOT' programme could uncover 440000 new diabetes, heart or kidney ... - Medical Xpress

Leicester researchers believe a new health MOT-style programme for over-40s is likely to uncover more diabetes, kidney or heart patients than expected.

University of Leicester researchers have found that the NHS Health Check Programme is likely to find 440,000 people each year who have diabetes or chronic kidney disease or who are at high risk of cardiovascular disease or diabetes.

Researchers from the Diabetes Research Unit based at the Leicester Diabetes Centre, within the University of Leicester, have published their study Joint Prevalence of Diabetes, Impaired Glucose Regulation, Cardiovascular Disease Risk and Chronic Kidney Disease in South Asians and White Europeans in the journal PLOS ONE.

The paper sheds light on the numbers of people in the general population who have diabetes or chronic kidney disease, or are at high risk of developing diabetes or cardiovascular disease.

These are the conditions which the NHS Health Check aims to identify in 40 to 74-year-olds. The programme began in 2009 and is being introduced across the UK over five years.

Initial estimates from the Department of Health suggested that the programme would detect at least 20,000 cases of diabetes or kidney disease – but the Leicester researchers believe this figure would be at least 158,000.

In addition, the researchers found that the total number of people likely to be diagnosed with diabetes or kidney disease or found to be at risk of diabetes or cardiovascular disease following the health check would be 440,000.

This would mean more patients than expected will require support and treatment from general practices around the UK – potentially increasing the workload of GP surgeries but also increasing the potential benefit and impact of the programme.

The study was led by Professor Kamlesh Khunti, Professor of Primary Care Diabetes and Vascular Medicine and Professor Melanie Davies Professor of Diabetes Medicine and Honorary Consultant, University Hospitals of Leicester, both from the University of Leicester's Diabetes Research Unit. The analysis was carried out by Dr Danielle Morris within their research group.

The researchers looked at patients taking part in a study led by Professor Khunti and Professor Davies which screened individuals from the general population for diabetes and vascular disease.

The researchers used the proportion of new patients discovered within Leicester sample to calculate the proportion of patients likely to be identified by the NHS Health Checks each year.

Professor Khunti said: "This study shows that a high proportion of people attending for the NHS Health Check Programme will have diabetes or chronic kidney disease or be at high risk of diabetes or cardiovascular disease.

"Overall this will lead to better prevention and management of these people with the potential to improve longer term outcomes. However, general practices implementing the programmes in their surgeries have already noticed an enormous increase in workload as a result of the NHS Health Check Programme."

Bridget Turner, Director of Policy and Care Improvement at Diabetes UK, said: "This research highlights the enormous potential of the NHS Health Check for identifying those at high risk of Type 2 diabetes and other health conditions, as well as diagnosing those people who have Type 2 diabetes and do not know it. This is why it is so disappointing that the implementation of the programme has been extremely patchy, with some areas of the country carrying out virtually no checks.

"The responsibility for commissioning the NHS Health Check will shift to local authorities in April. This is a real opportunity to for local government to make a difference and we look forward to working with them to help make sure the programme is finally implemented properly. We have been putting pressure on the Government to ensure that this happens through the new systems of accountability."

The work was supported by funding from the Department of Health, the University Hospitals of Leicester Diabetes Research Fund, Diabetes UK, the National Institute for Health Research Collaboration for Leadership in Applied Health Research and Care - Leicestershire, Northamptonshire and Rutland (NIHR CLAHRC – LNR) and The NIHR Leicester-Loughborough Diet, Lifestyle and Physical Activity Biomedical Research Unit.

More information: Plos One, "Joint Prevalence of Diabetes, Impaired Glucose Regulation, Cardiovascular Disease Risk and Chronic Kidney Disease in South Asians and White Europeans"Kamlesh Khunti, Claire L. Weston, Laura J. Gray Danielle H. Morris, David R. Webb, Melanie J. Davies, January 30, 2013

Link: Calcium supplements: A risk factor for heart attack?

Analysts study hazards for pregnancy-related diabetes - KSBY San Luis Obispo News

Research in excess of one-million females identifies pregnancy-related conditions that raise the risk for diabetes. Researchers in Canada viewed the medical records in excess of one-million expectant mothers. They noted which girls developed high blood pressure during pregnancy, or gestational diabetes, and then followed their health for years after their pregnancy. They found women who had high blood pressure during pregnancy had double the danger for diabetes in comparison to pre-eclampsia was not developed by women who. Women with both pre-eclampsia and gestational diabetes had a times higher risk for developing diabetes after pregnancy.

Lilly reports excellent results from two trials of diabetes medicine - Reuters

Tue Apr 16, 2013 9:06am EDT (Reuters) - Eli Lilly and Co said two additional late-stage studies evaluating its experimental diabetes drug dulaglutide met the main goal of minimizing hemoglobin A1c levels, a measure of blood sugar. Along with good results from three other late-stage studies introduced in October, a marketing application will be supported by the data for dulaglutide, Lilly said in a record. In the study called AWARD 2, the company explained a mg dose of its medicine proved more advanced than Sanofi's Lantus, at 52 weeks in type 2 diabetes patients, that are already on two different diabetes medications, metformin and glimeperide. Dulaglutide also trumped insulin lispro, in combination with Lantus, at 26 days of therapy in research dubbed as AWARD 4, Lilly said. The business said the most frequently reported adverse events were intestinal. In October, Lilly reported positive results of the other three studies where dulaglutide was compared with other diabetes medications. Lilly's stocks closed at $56.49 on Monday on the Newest York Stock Exchange. (Revealing By Pallavi Ail in Bangalore; Editing by Supriya Kurane)

Testing younger men for prostate cancer could lower deaths by not exactly HALF - Daily Mail

UPDATED: 05:39 EST, 17 April 2013 Offering tests to men within their late forties could reduce prostate cancer deaths by half, say experts. Prostate specific antigen (PSA) screening is employed to detect prostate cancer, but remains controversial, because it became popular long before there is considerable evidence to prove its worth. It can also be unreliable, giving false excellent results which can cause anxiety and end up in unnecessary treatment. Prostate cancer can be quite a source of anxiety for middle aged and older men As yet, the most up-to-date study found that prostate cancer screeningA decreased deaths by 20 per cent. But, with this came a high rates of unwanted therapy. Data indicated that to save lots of one life, almost 50 cases would have to be treated. In 2010, once the UK National Screening Committee in England last analyzed medical data, it decided that the national screening program shouldn't be introduced. Nevertheless now Swedish analysis, published in the BMJ, has discovered that if testing was wanted to males aged between 45 and 49, it'd predict nearly 50% of all cases. Analysts examined a report carried out between 1984 and 1974 concerning 21,277 Swedish males aged between 27 and 52. All the men had given blood samples at the start of the analysis. The researchers used these stored examples to perform PSA tests. Research indicates that screening males aged between 49 and 45 for prostate cancer (made) can save many lives They then checked to see if the PSA reading predicted whether or not they developed prostate cancer. These results were then used by the researchers to work out the very best age where men should be tested. They discovered that testing underneath the age of 45 found too few deadly cancers. Prostate cancer may be the most common cancer in men in the united kingdom A lot more than 40,000 new cases diagnosed each year. Symptoms include a difficulty passing urine, a need to frequently pass urine or having to rush to the toilet. PSA is just a protein produced by both normal and cancerous prostate cells But a high level of PSA could be a indication of cancer A PSA reading higher than four, but less than 10 is normally as a result of harmless enlarged prostate A reading higher than 10 may also just be a a symptoms of benign prostate disease The higher the degree of PSA, the more likely it's to be cancer And delaying assessment until after age 50 missed too many. Testing between the ages of 45 and 49 noticed 44 per cent of the cancers that turned fatal. In the analysis, 1,369 of the guys had prostate cancer, 241 had advanced disease and 162 died as a result. The research stated that all men ought to be provided a PSA test in their mid-to-late 40s. They advised that those with a high PSA reading must return for treatment, assessments and surveillance if necessary. Individuals with normal results could wait another five to a decade because of their next PSA test. The study said: aAt least half all men can be identified as staying at low risk and probably need only three PSA checks in a lifetime.' 'This is likely to reduce the chance of overdiagnosis while still permitting early cancer detection among those most likely to gain from early diagnosis,' they say. Public Health England review data for testing every three years to make sure that the programs provided by the NHS are derived from the absolute most up-to-date information available. Prostate Cancer UK said more research efforts ought to be directed into locating a greater screening test for the condition.

Link: Health Highlights: April 17, 2013

7 people who presumably faked cancer for private gain - The Week Magazine

D Cancer is wanted by o one. In reality, there are many, many individuals who devote their lives to finding out how exactly to eliminate it from this world. Which is why, maybe, we unquestioningly think and do anything for those who are affected by the fatal disease. You had need to be very low to lie about something such as that. And yet... 1. The girl who allegedly faked cancer to invest in her heroine habitBrittany Ozarowski was allegedly recognized in September 2011 with stomach cancer in addition to period two ovarian cancer. 3 months later, the Medford, N.Y., resident miraculously beat chances and her disease a' simply to think it is get back in the shape of bone and brain cancer. The 21-year-old create a web site (which included the tagline "Help Save yourself My Life") and a donation-seeking Facebook site, placed contribution jars in 25 local business, and held a few fundraisers. But the money she gained didn't account her treatment at Memorial Sloan-Kettering, but, presumably, her heroine practice. Ozarowski's grandmother offered her home and gave her daughter $100,000. Her father apparently lowered his retirement account. But one-time well wishers became suspicious of the alleged con artist when she kept refusing help get to her doctors visits. Ozarowski was arrested on April 1 and is in jail, pending relationship. She's charged with grand larceny and perpetrating a scheme to defraud. 2. The lady who faked cancer to raise money for breast implantsJami Lynn Toler revealed to her friends, family, and Hallmark Hospice co-workers that she had breast cancer and would be starting a mastectomy and breast reconstructive surgery. Her mother setup a web site for her 27-year-old child in 2011 to gather donations for the surgeries. Toler supposedly raked in a lot more than $8,000 for her cause. Except there was no cancer eating away at her body. As an alternative, there is only the desperate requirement for a breast augmentation. The Phoenix person was arrested, and pleaded guilty to the charges. Included in a arrangement, Toler was sentenced in September 2012 to one year in jail and will also get 3 years probation and will need certainly to pay restitution. 3. The person who faked breast cancer to avoid his parole officerIn 2005, Brian Jeffrey Bonniewell was sentenced to ten years of probation and caught on a burglary charge. The Texas man had to meet along with his probation officer monthly but, apparently, by 2011 he had grown sick and tired of the commitment. Throughout his July meeting he offered his officer with a letter nevertheless he'd been diagnosed with breast cancer and could be undergoing radiation and chemotherapy treatments. He would no longer be able to attend the meetings. Unfortunately, the letter convinced several, and a was issued to the Texas Oncology South Austin for Bonniewell's medical records only to find a ' surprise a' no history of him at all. 4. The woman who faked pancreatic cancer to keep from her embezzlement schemeIt was around 2007 that the administration of the Imperial Point Animal Hospital in south Florida begun to be worried about the business's financial state. The numbers were not including. Nevertheless when the employers went to Kelly Lisa Duncan for solutions, these were diverted by way of a new horror: Duncan had pancreatic cancer. For three years, Veterinarian Robert Buzzetti and his spouse, Gina, stood by their colleague's side as she experienced her trial. It was strange, though. Her worst medical issues did actually flare up when Buzzetti asked to review payroll. Eventually, her act unraveled this season when she was captured doctoring the payroll records. The cancer Duncan believed to have was indeed merely a diversion from the embezzlement scheme she had been hard at work at since 2004. Over six years, she had siphoned of Aat least $647,800 from her employer. In 2011, the 46-year-old was caught and pleaded guilty to mail fraud. At that time, she faced no more than 41 months in prison. 5. The mother who faked her son's cancer to obtain medical benefitsIn 2008, British mom Emma La Garde took her child to a doctor after he complained of pains in his feet. The 7-year-old's checks were clear, however the event influenced Manhunter Garde to orchestrate a medical episode for her daughter that could carry on for four years. Mom of five cast medical papers, shaved her son's hair and eyebrows, and made him use a wheelchair in public areas and at school. Initially she said the boy was struggling with an autoimmune disease, but 2 yrs later she jumped his disease to lymphoma. With this specific ruse she was able to make tax exemptions and disability benefits, and also qualified for capital being an at-home caretaker. She were able to fraud more than $130,000, and reportedly used some of the money to invest in luxurious vacations, including anyone to Disney World, where she would push her wheelchair-bound child to the top of the line. She was charged and ultimately caught with one count of son or daughter cruelty and ten counts of fraud, among other activities. In November 2012, she was delivered to jail for 3 years and nine weeks. 6. The woman who faked leukemia to invest in her magnificent weddingIn 2010, Jessica Vega started telling friends, family, and her upstate New York community that she was dying of leukemia. In the weeks she had left, she said, she needed simply to marry Michael O'Connell, the daddy of her infant daughter, in a "dream wedding." Money, bands, dresses, $1,000 price of wine and snacks, and a time-share apartment in Aruba flowed in. Her tragic history was even found by way of a local paper. The couple married in-may 2010. Immediately after, the man went along to the paper with accusations on the story they released and he was consequently existing. The couple soon divorced, and by April 2011, Vega, then 25, was indicted on charges of fraud and grand larceny. The newlywed-and-divorced woman was required to pay significantly more than $13,000 back once again to her donors. But fear not, romantics, for this story features a happy ending. After Vega premiered from prison, she and O'Connell got in together because, hi, "you can't help who you love," she said. 7. The man who presumably faked his wife's death-by-cancer to report time off and moneyAt first it was merely a group Scott Wellington's wife within her chest. However the disease rapidly escalated. Over two-and-a-half years, Wellington's colleagues at C&M Machine Co. in New Hampshire followed combined with the harrowing story of a cancer diagnosis, a mastectomy, and, in the course of time, his young wife's untimely death. The C&M workers were heartbroken for Wellington and his four kids and offered him money to cover the medical costs and time off to care for his kids and attend his wife's medical treatments. Over Xmas he was were able to acquire a lot more than $7,000 in donations, and given at the very least three weeks of paid holiday. But Wellington's spouse was alive and well. Only if she opened a sympathy card that arrived at home she heard bout her fictionalized death. She instantly called the company and told them the reality. Wellington was arrested in May 2011 and was faced with two matters of theft by fraud. The 31-year-old pleaded not liable, but he could confront 15 years in jail if convicted. Sources: CBS News,AThe Daily Mail,AThe Frisky, Huffington Post, Jezebel,ANBC Information, Sun Sentinel,AUnion Chief, UPI.com

More Info: Nike Studio Wrap: shoes for Pilates and Yoga, now with new design

Individual navigators at Allegiance Health help ease the shock of a diagnosis - The Jackson Citizen Patriot - MLive.com

Her co-worker, Lil McGaffigan, added, aWhen you're told you've cancer, you canat method yet another word.a And thatas why these women play this kind of crucial part at Allegiance, supporting people clinically determined to have cancer understand the medical program. Because it includes physicians from many areas, doctors to radiologists to oncologists it is an unwieldy system, mentioned Karen Yacobucci, executive director of Cardiovascular and Oncology Services at Allegiance. Whilst the average number of cancer patients living in Jackson County has remained at about 800 for every of the last three years, Yacobucci said Allegiance treated nearly 1,000 new cancer cases in 2012, areflective of our regional take of patients from outside Jackson County.a McGaffigan has been a navigator for significantly more than four decades, Petri for five months. aLil was a god-send,a Yacobucci said. aHer influence was so significant that we knew on board.a we needed someone else McGaffigan focuses on patients diagnosed with lung cancer, Petri on patients with breast cancer, the 2 largest groups of patients. Other cancers are divided between the girls. Barriers are broken down by awe help to care as advocates for the patient,a McGaffigan said. Because both are nurses a' an Allegiance dependence on the positioning a' the ladies might help explain from what doctors believed to insurance concerns. Bobbi Flinn, 64, of Jackson had a lumpectomy at Allegiance a year ago and hadnat decided if she'd have chemotherapy at Allegiance or an hospital, which she required another opinion. However the follow-up call from one other health system made Flinn aalmost hysterical. It absolutely was the first day I had been alone after surgery and I get this call about another surgery. I called my cousin in hysterics and she said to try and remember the girl I talked with at Allegiance. I said, aOh yes, Lil.aa Flinn had talked to McGaffigan before her surgery and was told to publish down her phone number and name and tuck it into her cancer file ajust in case.a aLil calmed me down, never said anything bad in regards to the other hospital, viewed my files and she was very reasonable, very positive in addition to loving,a Flinn said. aMy man frequently said he wonders if Lil goes home during the night and knows exactly what a difference she makes in the lives she touches.a McGaffigan and Petri are well conscious of the way the shock of a cancer diagnosis thinks since each has received it. Petri is really a breast cancer survivor, McGaffigan is really a two-time cancer survivor. aI never heard another word the doctor said,a McGaffigan said concerning the diagnosis. Her husband was with her, thankfully, so he was in a position to explain the medical plan to her. As individual navigators, some of the work is calling patients, some seeing them face-to-face in the Gayle Jacobs Cancer Center. They have also learned that in this economy, some people canat make their health their No. 1 priority, even a cancer diagnosis. aIf they canat work, they canat put food on the table,a McGaffigan said. aThey have therefore many financial problems and to increase cancer to the mix can be frustrating for them. It is quite humbling for us.a

Scientists find nanodiamonds can increase performance of...

(Click for information) Recently, doctors have begun to categorize breast cancers in to four main groups according to the genetic makeup of the cancer cells. Which group a cancer falls in to usually determines the very best way of treatment. But cancers in one of the four groups a' named "basal-like" or "triple-negative" breast cancer (TNBC) a' have now been especially difficult to deal with simply because they usually do not respond to the "receptor-targeted" remedies that are usually successful in treating other types of breast cancer. TNBC is commonly more intense compared to the other types and more likely to recur, and can also have a higher death rate. Nanodiamonds are 6 and between 4 nanometers in diameter and are shaped like small soccer balls. Byproducts of conventional mining and refining procedures, the particles can develop groups following drug binding and have the opportunity to precisely supply cancer drugs to tumors, significantly improving the drugs' desired result. In the UCLA study, the nanodiamond supply system has had the opportunity to home in on tumefaction masses in mice with multiple negative breast cancer. "This study shows the usefulness of the nanodiamond as a targeted drug-delivery agent to a cancer site," said Ho, who is also an associate of the California NanoSystems Institute at UCLA, UCLA's Jonsson Comprehensive Cancer Center and the UCLA Department of Bioengineering. "The agent we've developed reduces the harmful unwanted effects which can be associated with treatment and mediates substantial reductions in tumefaction size." The group mixed several crucial cancer-fighting components on the nanodiamond floor, including Epirubicin, a very dangerous but widely used chemotherapy drug that is frequently applied in conjunction with other cancer drugs. The brand new element was then bound to a material coated with antibodies that were focused toward the epidermal growth factor receptor, which is very concentrated on the materials of TNBC cells. The resulting agent is a drug-delivery system called a nanodiamond-lipid cross element, or NDLP. The agent was proven to particularly decrease tumefaction growth and eliminate the harmful negative effects of cancer therapy, when tested on mice. Due to the toxicity, Epirubicin, when administered alone may cause severe unwanted effects, such as heart failure and paid off white blood cell count, and it has been linked to a heightened risk for leukemia. In the study, all of the rats that have been provided Epirubicin alone died well before the conclusion of the study. But all the rats given Epirubicin through the specific NDLPs survived the treatment, and a few of the cancers actually regressed until these were no longer visible. "Triple-negative breast cancer is often very aggressive and difficult to deal with, making aggressive chemotherapy a said Dr. Edward K. Chow, co-first author of the study and an assistant professor at the Cancer Science Institute of Singapore. "The targeting and therapeutic efficiency of the nanodiamond-lipid agents were quite remarkable. The multiple tumefaction regression and improved medicine threshold are promising signals for the continued growth of the nanodiamonds toward medical translation." The investigation group has become studying the efficacy and safety of the NDLPs in larger animals. Extra research objectives include determining whether nanodiamonds may boost the tolerance of a broad spectrum of highly toxic drug ingredients, which may increase current treatments and results. These findings will serve as precursors for individual studies, the researchers said. "The nanodiamond-lipid hybrid developed in this study is just a modular platform," explained Laura Moore, a student in Ho's laboratory and a co-first composer of the study. "Therefore, we are able to simply bind a wide spectral range of targeting antibodies and drug substances to deal with several diseases." Dr. No-Hee Park, dean of the UCLA School of Dentistry, observed that the investigation provides a basis for future clinical applications. "This pioneering research done by Dean Ho and his group supplies a better comprehension of the functions of the nanodiamond material to deal with many diseases," Park said. "Their work is of paramount importance." Other writers of the analysis were Professor Eiji Osawa of the NanoCarbon Research Institute in Nagano, Japan, and Professor J. Michael Bishop of UC Bay Area. Laura Moore is currently at Northwestern University. The study was supported by the National Cancer Institute, the National Science Foundation, the Wallace H. Coulter Base, the V Foundation for Cancer Research, the Society for Laboratory Automation and Testing, the George Williams Hooper Basis, the American Cancer Society, Beckman Coulter, the European Commission, the Cancer Science Institute of Singapore, and the Singapore Ministry of Education Academic Research Fund.

Via: Australian scientists claim to have cured to breast cancer in mice

Bare warehouse to be converted for cancer fundraiser - Topeka Capital Journal

Get SpottedA Please Note: You could have handicapped JavaScript and/or CSS. While this information content will be accessible, specific operation is inaccessible. Miss to News A back next A 2013 Gold Lake Prom 2013 Rossvile Prom Hayden High School Prom Sliver River Prom 2013 Koyotes Heroes Evening 2013 Koyotes vs KC Renegades The Split Room: Bluegrass and Apple Jam Koyotes Personalities Night at the Expo Washburn Rural Middle College Prom

More Info: Newspaper urges to eat chicken to avoid huge losses by avian influenza

NBA great visits Chillicothe to share diabetes awareness message - Chillicothe Gazette

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Via: Decisions, Decisions: Work Out or Fix a Meal?

NY person faked cancer to feed heroin habit, prosecutors say - Fox News

Revealed April 11, 2013 Associated Press KEY ISLIP, N.Y. a AA Long Island girl faked cancer and sought contributions from store consumers and others to guide her heroin habit, an indictment unsealed Wednesday so-called, and a prosecutor called the plot "a wretched scam." Brittany Ozarowski, 21, formerly of Selden, was billed in Suffolk County with 24 matters including grand larceny in the 3rd stage. Prosecutors said Ozarowski remaining donor containers at Nassau and Suffolk county organizations and struck up store buyers for the money. She also conned her grandmother and father, who sold her home and offered Ozarowski more than $100,000, District Attorney Thomas Spota said. A despicable scam was perpetrated by "this defendant. ... There was no cancer, no chemotherapy or radiation. All there was was heroin and more heroin," he said. Ozarowski's lawyer George Duncan said Wednesday he'd not yet seen the charges and could not comment. Spota said small-business owners contributed a lot more than $600 in present certificates and Ozarowski founded a PayPal account and an internet site with a that pleaded, "Help Save My Life." "She told companies that she was suffering from brain and bone cancer, that the illness was spreading to her thyroid and her stomach," Spota said at a news conference. "She told some individuals that she just learned mental performance cancer was inoperable." Spota said Ozarowski was sooner or later found each time a man she had asked for cash became suspicious and asked for her doctor's name, which she refused to supply. The person called the district attorney's office.

More Info: First case of pregnancy after transplantation of the uterus of a deceased

Most Effective PTSD Therapies Are Not Being Widely Used, Researchers Find

Post-traumatic stress disorder affects nearly 8 million adults in any given year, federal statistics show. Fortunately, clinical research has identified certain psychological interventions that effectively ameliorate the symptoms of PTSD.  But most people struggling with PTSD don't receive those treatments, according to a new report published in Psychological Science in the Public Interest.

In the report, internationally renowned trauma expert Edna Foa of the University of Pennsylvania and a team of distinguished psychological scientists review studies describing interventions that can effectively treat PTSD.

Foa, an Association for Psychological Science fellow, pioneered the use of prolonged exposure therapy (PE), in which patients approach - in both imaginary and real-life settings - situations, places, and people they have been avoiding. The repeated exposure to the perceived threat disconfirms individuals' expectations of experiencing harm and, over time, leads to a reduction in their fear.  Foa authored the new report with Seth Gillihan of Haverford College in Pennsylvania and Richard Bryant of the University of New South Wales in Sydney, Australia.

Over years of testing, PE and other forms of cognitive behavioral therapy have proved highly effective in addressing the distress and dysfunctional problems that trauma victims experience. However, the majority of mental health professionals do not use such evidence-based treatments (EBTs) when working with patients suffering from PTSD, the researchers write.

Many clinicians believe that good psychotherapy should be individualized and should focus on the underlying causes of one's problems and symptoms. But studies show scant evidence that psychodynamic therapy - which focuses on such issues as difficult childhood relationship with parents - effectively eases PTSD symptoms, according to the report.

Foa and her colleagues say their findings are important given that traumatic events such as natural disasters, terrorist attacks, and gun violence are on the rise.

Recent history offers prime examples of that trend. More than 273,000 Iraq and Afghanistan war veterans have sought treatment for post-traumatic stress disorder over the past decade, the U.S. Department of Veterans Affairs reports. Researchers at Harvard Medical School found that at least one-third of residents in the path of Hurricane Katrina suffered some form of post-traumatic stress after the 2005 storm. And in the two months following last year's tragic mass shooting at Sandy Hook Elementary School in Connecticut, more than 16 percent of Newtown, Connecticut's police force had missed work because of PTSD-related issues, according to news reports.

"Not counting traumatic events that are experienced by individuals as opposed to entire populations, the number of people who need help for their PTSD and related symptoms is mind boggling," Foa and her co-authors write.

"Thus PTSD treatment researchers are acutely aware of the tremendous need to disseminate effective treatments widely such that patients have access to them, and are also aware of the challenges to successfully meet this need."

The report, "Challenges and Successes in Dissemination of Evidence-Based Treatments for Posttraumatic Stress: Lessons Learned From Prolonged Exposure Therapy for PTSD," is accompanied by an editorial from Bradley E. Karlin and Madhulika Agarwal of the U.S. Department of Veterans Affairs Central Office in Washington, DC.

Psychological Science in the Public Interest is a journal of the Association for Psychological Science. It publishes an eclectic mix of thought-provoking articles on the latest important advances in psychology. For a copy of the article "Challenges and Successes in Dissemination of Evidence-Based Treatments for Posttraumatic Stress: Lessons Learned From Prolonged Exposure Therapy for PTSD" and access to other Psychological Science in the Public Interest research findings, please contact Anna Mikulak at 202-293-9300 or .

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Coffee Extract Proven to Combat Diabetes - Newsmax Health

An all-natural extract from unroasted coffee beans might be a instrument in preventing the uncontrolled blood sugar levels characteristic of diabetes, a small, original new research indicates. Study done in India on normal-weight participants with normal blood sugar (or blood sugar) levels unearthed that different doses of products containing green coffee extract all decreased blood sugar, with higher doses associated with larger drops. "If this may affect a standard person's [glucose levels], then it should be better yet for diabetics because they have a problem," said research writer Joe Vinson, a of chemistry at the University of Scranton, in Pennsylvania. "The green coffee [extract] is the greatest aspect of coffee to be studied, I think." The study was financed by Applied Foods of Austin, Texas, suppliers of the green coffee extract. Vinson was planned to provide the investigation, done in India, this week at a gathering of the American Chemical Society in New Orleans. Studies presented at scientific meetings are an average of not yet peer-reviewed and results are considered preliminary. About 26 million Americans have diabetes, that is the most common form, according to the U.S. Centers for Infection Get a grip on and Prevention. Diabetes is connected to problems including kidney failure, cardiovascular disease, blindness and lower-leg amputations. The studies did not prove that coffee caused these health outcomes, but simply that a connection existed. Vinson's research analyzed 30 men and women of normal weight who did not have diabetes. They got supplements containing between 100 milligrams (mg) and 400 mg of the inexperienced coffee extract in a pill with water, followed by glucose tolerance tests at many points afterward. All doses of the extract did actually lower participants' blood sugar, Vinson said, but an amount of 400 mg was associated with a 24 percent drop 30 minutes after getting the extract and a percent drop 120 minutes later. Vinson said he feels the sugar-lowering aftereffects of green coffee extract are because of its concentration of chlorogenic acids a' anti-oxidants present in apples, cherries, apples and other fruits and vegetables. Large temperatures used to roast coffee beans generally break up chlorogenic chemicals, he said, so coffee beverages contain less of them than ingredients found in supplements. "This research had firmly standard [participants], nonetheless it has a large amount of potential for diabetes [control]," Vinson said. "It is just a fairly inexpensive treatment and might cost less than a dollar or two daily a less than a coffee at Starbucks." But John Anderson, M.D., president of science and medicine at the American Diabetes Association, cautioned against achieving any firm conclusions from the investigation. Green coffee extract would need to be studied thoroughly before it could be provided as a potential prevention or remedy for diabetes, he explained. "To say that something can avoid or delay diabetes is practically impossible to demonstrate until they are prepared to spend hundreds of millions of dollars on research. This wants rigorous medical experiments to prove," Dr. Anderson said. "This is just [30] individuals, and all they did was look at a glucose tolerance test. I think it's interesting, but I don't think we really know anymore than that." A HealthDay

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Jack Hoffman Touchdown: 7-Year-Old Brain Cancer Individual Scores In Nebraska... - Huffington Post

An earlier choice for most heartwarming sports second of the entire year occurred during Nebraska's spring basketball game on Saturday. Wearing a jersey and helmet, 7-year-old brain cancer patient Jack Hoffman took a from quarterback Taylor Martinez and left every Cornhusker person in his tracks. Hoffman ran 69 meters for the touchdown, the game's final score, and recognized with the entire Nebraska team in the end zone. A group of over 60,000 at Memorial Stadium cheered him on, the Washington Post reported. "It was awesome," Hoffman said afterward, via Omaha.com. In April 2011, Hoffman was clinically determined to have a brain tumefaction, based on the Daily Nebraskan. He has had two procedures since and is now on a rest for two days from a 60-week chemotherapy course, per ESPN.com. Whilst the movie of his touchdown began to make its away around the web, several responded to the time on Twitter. Connected on HuffPost:

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Reasonable Drinking OK for Breast Cancer Survivors? - WebMD

Women who eat up alcohol in moderation have lower danger of heart disease death, experts increase WebMD Information from HealthDay By Kathleen Doheny HealthDay Writer THURSDAY, April 9 (HealthDay News) -- Women who have survived breast cancer can consume alcohol in moderation, new research shows. General, mild drinking before or following a diagnosis of breast cancer does not appear to have a damaging effect on survival from breast cancer, the analysis found. When researchers looked only at moderate drinking before a cancer diagnosis, it absolutely was linked with a 15 percent lower threat of dying from breast cancer compared to nondrinkers, said research author Polly Newcomb, head of the cancer prevention software at the Fred Hutchinson Cancer Research Center, in Seattle. Women who drank averagely before or after a breast cancer prognosis had a percent lower risk of death from cardiovascular infection and a percent lower risk of death from other causes during the 11 years the girls were used. Newcomb's team found an organization, and not just a cause-and-effect relationship, for moderate alcohol consumption and survival. The results ''should be reassuring to women," said Newcomb, who is also a study professor at the University of Washington. It is known that alcohol consumption does raise the threat of getting breast cancer. "Our emphasis was on breast cancer survivors," Newcomb said, as they often wonder whether they should consume alcohol or not. Women were evaluated nearly 23,000 by newcomb. All reported on their intake of alcohol before examination, and about 5,000 reported on their intake after. The follow-up was just over a decade, an average of. The research was printed April 8 in the Journal of Clinical Oncology. Women were evaluated by newcomb participating research of risk facets for breast cancer sponsored by the U.S. National Cancer Institute (NCI). It started in 1988. Small follow-up study of drinking practices after examination included about 5,000 girls and was conducted from 1998 to 2001. Newcomb said, those that participated were similar with regards to age and other qualities than the non-responders from the larger sample, suggesting the results are reliable, although the post-diagnosis sample of survivors was smaller. Throughout the follow-up period, 7,780 deaths happened, including nearly 3,500 from breast cancer. Newcomb looked over deaths and alcohol habits. Women who had three to six drinks per week -- considered average drinking -- before examination had in regards to a 15 percent lower danger of death from breast cancer than nondrinkers, she found. What might explain the difference in alcohol's effect -- that it raises the danger of getting the disease but does not affect the general success? Alcohol intake is considered to improve the threat of getting breast cancer as a result of increases in estrogen production, Newcomb said. It could be the type of breast cancer almost certainly can be found among women who drink might merely be much more tuned in to treatments that lower estrogen.

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Pre-pregnancy body fat, in-pregnancy weight gain, and gestational diabetes ... - EurekAlert (press release)

A new study shows that a woman's pre-pregnancy body fat (adiposity), in-pregnancy weight gain, and presence of gestational diabetes mellitus (GDM) can all combine to steeply increase the risk of giving birth to large-for-gestational age (LGA) babies to different degrees in white non-Hispanic, black non-Hispanic, White Hispanic, and Asian women, with the highest combined risk being in White non-Hispanic women. The research is published in the journal Diabetologia (the journal of the European Association for the Study of Diabetes) and is led by Dr Katherine Bowers and Dr Cuilin Zhang at the Eunice Kennedy Shriver National Institute of Child Health and Human Development at the National Institutes of Health (USA), and colleagues.

The race-specific joint effects of three major risk factors on risk of LGA births have previously not been comprehensively analysed. In this study, Bowers and colleagues analysed data from a major US study (the Consortium on Safe Labour study), comprising 105,985 pregnancies in the period 2002.

The researchers found that greater pre-pregnancy adiposity, pregnancy weight gain and GDM were all independently associated with increased risk of giving birth to an LGA infant across all races (except GDM among non-Hispanic whites), in both underweight and normal-weight women. Among non-Hispanic white (11-fold increased risk), non-Hispanic black (7-times) and Hispanic women (10 times), the three-factor joint effect was associated with substantially increased odds of LGA babies. However, for Asian women the joint effect of all three factors (five times increased risk) was approximately the same as any combination of two factors; whereas for Hispanic and non-Hispanic white women, the association with LGA delivery more than doubled when comparing three risk factors with two.

Asian women had the highest proportion of LGA births (12.0%) compared with black (10.6%), Hispanic 10.6%) and white non-Hispanic (9.7%) women. Asian women were also the most likely to have GDM (9.0%), compared with Hispanic women (6.0%) and white non-Hispanic and black non-Hispanic women (both 3.4%).

The authors say: "Variations in the influence of GDM and weight characteristics on LGA by race may be due to differences in metabolism exemplified by variation in body composition and/or genetics."

They further point out that regional fat distribution can vary between women across these races, and the study shows that baseline (pre-pregnancy) levels of overweight and obesity also varied widely depending on race. Black women had the highest levels (28% obese, 26% overweight), then Hispanic (18% obese, 27% overweight), then White non-Hispanic (15% obese, 20% overweight), and lastly Asian (9% obese, 14% overweight).

The authors conclude: "In this large multi-race/ethnicity cohort in the USA, we observed that GDM was significantly associated with risk of women giving birth to macrosomic and LGA infants, even among normal-weight and underweight women. More importantly, this association was significantly modified by prepregnancy BMI, pregnancy weight gain and race. The joint effects of pre-pregnancy obesity, weight gain during pregnancy and GDM on fetal growth also varied by race/ethnicity. These results suggest that a woman's race may be an important consideration when developing prevention strategies for excess fetal growth in women with GDM."

They add that it is important that the findings are replicated in future controlled studies before any concrete recommendations are issued. They say: "Given replicated evidence, especially white, but also black and Hispanic women would benefit greatly by focusing on a single factor, given the challenge of addressing pre-pregnancy weight and then weight gain and GDM together in pregnancy. Asian women would benefit most by addressing their GDM in addition to weight gain in pregnancy or entering pregnancy at a lower BMI."

AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.

A new study shows that a woman's pre-pregnancy body fat (adiposity), in-pregnancy weight gain, and presence of gestational diabetes mellitus (GDM) can all combine to steeply increase the risk of giving birth to large-for-gestational age (LGA) babies to different degrees in white non-Hispanic, black non-Hispanic, White Hispanic, and Asian women, with the highest combined risk being in White non-Hispanic women. The research is published in the journal Diabetologia (the journal of the European Association for the Study of Diabetes) and is led by Dr Katherine Bowers and Dr Cuilin Zhang at the Eunice Kennedy Shriver National Institute of Child Health and Human Development at the National Institutes of Health (USA), and colleagues.

The race-specific joint effects of three major risk factors on risk of LGA births have previously not been comprehensively analysed. In this study, Bowers and colleagues analysed data from a major US study (the Consortium on Safe Labour study), comprising 105,985 pregnancies in the period 2002.

The researchers found that greater pre-pregnancy adiposity, pregnancy weight gain and GDM were all independently associated with increased risk of giving birth to an LGA infant across all races (except GDM among non-Hispanic whites), in both underweight and normal-weight women. Among non-Hispanic white (11-fold increased risk), non-Hispanic black (7-times) and Hispanic women (10 times), the three-factor joint effect was associated with substantially increased odds of LGA babies. However, for Asian women the joint effect of all three factors (five times increased risk) was approximately the same as any combination of two factors; whereas for Hispanic and non-Hispanic white women, the association with LGA delivery more than doubled when comparing three risk factors with two.

Asian women had the highest proportion of LGA births (12.0%) compared with black (10.6%), Hispanic 10.6%) and white non-Hispanic (9.7%) women. Asian women were also the most likely to have GDM (9.0%), compared with Hispanic women (6.0%) and white non-Hispanic and black non-Hispanic women (both 3.4%).

The authors say: "Variations in the influence of GDM and weight characteristics on LGA by race may be due to differences in metabolism exemplified by variation in body composition and/or genetics."

They further point out that regional fat distribution can vary between women across these races, and the study shows that baseline (pre-pregnancy) levels of overweight and obesity also varied widely depending on race. Black women had the highest levels (28% obese, 26% overweight), then Hispanic (18% obese, 27% overweight), then White non-Hispanic (15% obese, 20% overweight), and lastly Asian (9% obese, 14% overweight).

The authors conclude: "In this large multi-race/ethnicity cohort in the USA, we observed that GDM was significantly associated with risk of women giving birth to macrosomic and LGA infants, even among normal-weight and underweight women. More importantly, this association was significantly modified by prepregnancy BMI, pregnancy weight gain and race. The joint effects of pre-pregnancy obesity, weight gain during pregnancy and GDM on fetal growth also varied by race/ethnicity. These results suggest that a woman's race may be an important consideration when developing prevention strategies for excess fetal growth in women with GDM."

They add that it is important that the findings are replicated in future controlled studies before any concrete recommendations are issued. They say: "Given replicated evidence, especially white, but also black and Hispanic women would benefit greatly by focusing on a single factor, given the challenge of addressing pre-pregnancy weight and then weight gain and GDM together in pregnancy. Asian women would benefit most by addressing their GDM in addition to weight gain in pregnancy or entering pregnancy at a lower BMI."

AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.

Jack Hoffman: Nebraska Allow 7-Year-Old Cancer Patient Rating...

Seven-year-old Jack Hoffman befriended Rex Burkhead all through his struggle with brain cancer. On Saturday, Nebraska produced him on the industry to perform for a touchdown carrying Burkheadas No. 22 in their Spring Game. Sports can be bad, however they can also bring occasions like this.

7-Year-Old Cancer Patient Scores Touchdown for Nebraska Cornhuskers - ABC News (blog)

The biggest thing to happen at the Nebraska Cornhuskers' spring football game Saturday was the smallest person on the field, a 7-year-old boy with brain cancer.

That boy, Jack Hoffman, ran 69 yards during the game's fourth quarter to score the scrimmage's final touchdown and become the game's leading rusher.

Jack, of Atkinson, Neb., was diagnosed with brain cancer in April 2011 and is undergoing a 60-week chemotherapy program.  Now on a two-week break from the treatment, Jack and his family received a call from the University of Nebraska's athletic department inviting them to Saturday's game at Memorial Stadium for a special play.

"This was kind of an impromptu idea by the University of Nebraska football staff and they just wanted to provide a once-in-a-lifetime opportunity for Jack," his dad, Andy Hoffman, said today on "Good Morning America."

Wearing a mini-Cornhusker uniform with the No. 22 of his idol, star Nebraska running back Rex Burkhead, Jack took the field before more than 60,000 fans at Memorial Stadium.

The mini-me, instant football star emerged from a huddle with players nearly triple his size and lined up for the play after a little direction from his new teammates.  He took a handoff from quarterback Taylor Martinez and then ran clear down the field and into the end zone.

As the referee lifted his arms in the touchdown sign, Jack was mobbed by players from both sidelines and lifted on the shoulders of Nebraska's star players.

Jack is a lifelong Cornhusker fan who went to his first game on his fifth birthday.  Just before his second brain surgery, in September 2011, his family reached out to the university and arranged for Jack to meet Burkhead and tour the stadium of the team he so loves, according to the family's foundation's website.

That meeting turned into a friendship with Burkhead that continues to this day.  Burkhead wears a wristband that says, "Team Jack-Pray," and is also a major supporter of the foundation started by the Hoffman family to fund pediatric brain cancer research, the Team Jack Foundation.

Jack's touchdown run that came from his initial meeting with Birkhead has now garnered even more attention for the family and their foundation.  It was the number one "Play of the Day" video on ESPN and has been viewed more than two million times on YouTube.

"We just kind of thought we were going to go down there and do that [the touchdown play]," said Hoffman.  "Little did we know that when we signed up for that it was going to turn into this big national story so it's kind of overwhelming, actually, for our family."

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